MED1

Across TCGA patient cohorts, MED1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,402 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED1-associated proteins across cancer lineages are RIF1_S782, SF3B3, and SNRPD2. Each is linked with MED1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MED1-to-partner and partner-to-MED1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED1 versus RIF1_S782 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED1→partner) and Y-score (partner→MED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIF1_S782 →	+0.610	+0.525	<.001	<.001	3	6
GBM	SF3B3 →	+0.322	+0.497	<.001	<.001	3	6
GBM	SNRPD2 →	+0.349	+0.479	<.001	<.001	3	6
LSCC	CPSF3 →	+0.259	+0.674	<.001	<.001	3	6
GBM	CSTF1 →	+0.316	+0.417	<.001	<.001	3	6
LSCC	DHX9 →	+0.312	+0.698	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,402 associations by consensus.

MED1 vs RIF1_S782 — LSCC

Explore this scatter interactively →