MED1

Across TCGA patient cohorts, MED1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,304 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED1-associated genes across cancer lineages are C1orf112, PHB, and LIN9. Each is linked with MED1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MED1-to-partner and partner-to-MED1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED1 versus C1orf112 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED1→partner) and Y-score (partner→MED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C1orf112 →	+0.658	+0.249	<.001	<.001	3	7
HNSC	PHB →	+0.572	+0.143	.006	<.001	3	6
LSCC	LIN9 →	+0.702	+0.224	<.001	<.001	3	6
OV	NME1 →	+0.633	+0.160	.001	.001	3	6
GBM	VRK1 →	+0.832	+0.317	<.001	<.001	3	6
LSCC	TMEM97 →	+1.330	+0.279	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,304 associations by consensus.

MED1 vs C1orf112 — LSCC

Explore this scatter interactively →