MED1

Across TCGA cell cohorts, MED1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,419 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Regulation of microtubule depolymerization, and Nuclear transport. Each is linked with MED1 in more than 16 cancer types. Because this analysis shows association rather than direction, both MED1-to-partner and partner-to-MED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by MED1-low versus MED1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED1→partner) and Y-score (partner→MED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DNA-templated transcription initiation →	+0.068	+0.987	<.001	.005	3	17
LUNG_NSCLC_LUSC	Regulation of microtubule depolymerization →	+0.090	+0.637	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.086	+1.315	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.086	+1.413	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.060	+1.252	<.001	<.001	3	17
SOFT_TISSUE	Heterochromatin formation →	+0.076	+0.980	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,419 associations by consensus.

DNA-templated transcription initiation by MED1 expression — STOMACH

Explore this box plot interactively →