MEAF6

Across TCGA cell cohorts, MEAF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,747 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MEAF6-associated GO terms across cancer lineages are DAMP biosynthetic process, Purine deoxyribonucleoside monophosphate biosynthetic process, and Protein localization to cilium. Each is linked with MEAF6 in more than 11 cancer types. Because this analysis shows association rather than direction, both MEAF6-to-partner and partner-to-MEAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAMP biosynthetic process grouped by MEAF6-low versus MEAF6-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEAF6→partner) and Y-score (partner→MEAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DAMP biosynthetic process →	+0.120	+0.728	.001	.007	2	12
PANCREAS	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.120	+0.728	.001	.007	2	12
LIVER	Protein localization to cilium →	+0.069	+0.544	<.001	.007	3	11
LARGE_INTESTINE	Intraciliary anterograde transport →	+0.094	+0.569	<.001	<.001	3	10
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.064	+0.923	<.001	<.001	2	11
BLOOD_Leukemia	Positive regulation of organelle assembly →	+0.038	+0.359	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,747 associations by consensus.

DAMP biosynthetic process by MEAF6 expression — PANCREAS

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