ME2P1

Across TCGA pan-cancer cohorts, ME2P1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ME2P1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ME2P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ME2P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUSC show a favorable association.

SKCM, TGCT, and KIRC are the cancer types where ME2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.922	0.853	.004	48	view →
TGCT	OS	Tertile	III,IV	0.501	1.000	.014	36	view →
KIRC	OS	Median	All	0.761	0.843	.009	23	view →
LUSC	DFS	Tertile	II,III,IV	0.711	0.541	.021	20	view →
COAD	DFS	Tertile	All	0.848	0.632	.002	18	view →
LIHC	DFS	Tertile	II,III,IV	0.286	0.450	.013	18	view →
SARC	OS	Tertile	All	0.408	0.638	.017	12	view →
ACC	OS	Tertile	IV	0.344	0.724	.038	12	view →
PCPG	OS	Tertile	All	0.828	0.968	.021	9	view →
KIRP	OS	Median	III,IV	0.700	0.375	.038	9	view →
STAD	OS	Tertile	IV	0.754	0.190	.038	6	view →
DLBC	DFS	Quartile	III,IV	0.070	0.803	.025	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ME2P1–SKCM (OS)

Open the SKCM breakdown →