Across TCGA patient cohorts, MDS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,151 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MDS2-associated GO terms across cancer lineages are Alpha-beta T cell activation, Antigen receptor-mediated signaling pathway, and B cell receptor signaling pathway. Each is linked with MDS2 in more than 21 cancer types. Because this analysis shows association rather than direction, both MDS2-to-partner and partner-to-MDS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MDS2→partner) and Y-score (partner→MDS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Alpha-beta T cell activation →	+0.060	+0.242	<.001	<.001	3	22
STAD	Antigen receptor-mediated signaling pathway →	+0.071	+0.268	<.001	<.001	3	22
STAD	B cell receptor signaling pathway →	+0.075	+0.246	<.001	<.001	3	22
STAD	T cell migration →	+0.076	+0.289	<.001	<.001	3	22
ESCA	Lymphocyte homeostasis →	+0.085	+0.265	<.001	<.001	3	22
LAML	Gamma-delta T cell activation →	+0.076	+0.392	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,151 associations by consensus.

Exploration

MDS2 survival (RNA) · tumor vs normal (RNA) · all MDS2 data types