Across TCGA pan-cancer cohorts, MDP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MDP1 data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MDP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MDP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, LSCC, and UCEC are the cancer types where MDP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.245	0.653	.025	22	view →
LSCC	DFS	Quartile	III,IV	0.553	1.000	.031	7	view →
UCEC	DFS	Median	III,IV	0.527	1.000	.049	4	view →
CCRCC	OS	Median	III,IV	0.962	0.798	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MDP1 tumor-vs-normal RNA expression · all MDP1 data types