Across TCGA patient cohorts, MDP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,160 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MDP1-associated GO terms across cancer lineages are Mitochondrial ribosome assembly, Tail-anchored membrane protein insertion into ER membrane, and Vesicle tethering to Golgi. Each is linked with MDP1 in more than 20 cancer types. Because this analysis shows association rather than direction, both MDP1-to-partner and partner-to-MDP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MDP1→partner) and Y-score (partner→MDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Mitochondrial ribosome assembly →	+0.044	+0.451	<.001	<.001	3	21
ESCA	Tail-anchored membrane protein insertion into ER membrane →	+0.048	+0.351	.002	<.001	2	21
UVM	Vesicle tethering to Golgi →	+0.070	+0.838	<.001	<.001	3	20
UVM	Peroxisome organization →	+0.034	+0.573	<.001	<.001	3	20
KIRP	Protein import into peroxisome matrix, substrate release →	+0.042	+0.295	<.001	<.001	3	20
UVM	Inner mitochondrial membrane organization →	+0.037	+0.581	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,160 associations by consensus.

Exploration

MDP1 survival (RNA) · tumor vs normal (RNA) · all MDP1 data types