Across TCGA patient cohorts, MDP1 mutation is significantly associated with the RNA expression of many other genes, with 646 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MDP1-associated genes across cancer lineages are RNU1-1, IGLVVI-22-1, and LINC02727. Each is linked with MDP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MDP1-to-partner and partner-to-MDP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MDP1→partner) and Y-score (partner→MDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-1 →	+0.345	+2.994	<.001	.003	3	2
BRCA	IGLVVI-22-1 →	+0.181	+8.467	<.001	<.001	3	1
BRCA	LINC02727 →	+0.070	+5.721	.001	.003	3	1
BRCA	LINC02297 →	+0.082	+5.683	<.001	.004	3	1
UCEC	LLPHP1 →	+0.107	+3.136	.001	.007	3	1
UCEC	GPR75-ASB3 →	+0.112	+3.676	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 646 associations by consensus.

Exploration

MDP1 survival (RNA) · tumor vs normal (RNA) · all MDP1 data types