Across TCGA patient cohorts, MDP1 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MDP1-associated genes across cancer lineages are G6PD, JNK2, and Tuberin. Each is linked with MDP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MDP1-to-partner and partner-to-MDP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MDP1→partner) and Y-score (partner→MDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	G6PD →	-0.361	-3.149	.033	.019	3	1
UCEC	JNK2 →	+0.224	+3.321	.031	.010	1	2
UCEC	Tuberin →	+0.402	+3.321	.004	.010	2	1
UCEC	VHL →	-0.941	-3.000	.008	.036	2	1
UCEC	14-3-3_zeta →	-0.217	-3.295	.045	.010	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

MDP1 survival (RNA) · tumor vs normal (RNA) · all MDP1 data types