MDN1

Across TCGA cell cohorts, MDN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,484 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MDN1-associated GO terms across cancer lineages are Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Recombinational repair, and DNA-templated DNA replication maintenance of fidelity. Each is linked with MDN1 in more than 19 cancer types. Because this analysis shows association rather than direction, both MDN1-to-partner and partner-to-MDN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by MDN1-low versus MDN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MDN1→partner) and Y-score (partner→MDN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.158	+1.332	<.001	<.001	3	20
BONE	Recombinational repair →	+0.111	+1.346	.001	<.001	3	19
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.150	+1.399	.001	<.001	3	19
BONE	Maturation of 5.8S rRNA →	+0.176	+1.494	<.001	<.001	3	19
BONE	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.178	+1.607	<.001	<.001	3	19
BONE	Maturation of LSU-rRNA →	+0.206	+1.582	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,484 associations by consensus.

Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by MDN1 expression — BONE

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