Across TCGA pan-cancer cohorts, MDM4P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MDM4P1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where MDM4P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MDM4P1 is over-expressed in tumor.

UCEC and LUSC are the cancer types where MDM4P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MDM4P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.100	.037	2	view →
LUSC	All	All	+0.030	.016	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MDM4P1 RNA expression & survival · all MDM4P1 data types