MDM1

Across TCGA patient cohorts, MDM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,734 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MDM1-associated proteins across cancer lineages are RCOR3, CAND1, and VEZF1. Each is linked with MDM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MDM1-to-partner and partner-to-MDM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MDM1 versus RCOR3 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MDM1→partner) and Y-score (partner→MDM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCOR3 →	+0.397	+0.377	.003	.005	3	5
OV	CAND1 →	+0.468	+1.026	<.001	<.001	3	5
HNSC	VEZF1 →	+0.466	+0.837	<.001	<.001	3	4
GBM	RSRC1 →	+0.281	+0.504	<.001	<.001	3	4
CCRCC	LAD1_T19 →	-1.034	-0.419	.001	<.001	3	4
UCEC	MDM1_S263 →	+0.693	+0.582	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,734 associations by consensus.

MDM1 vs RCOR3 — GBM

Explore this scatter interactively →