MDK

Across TCGA patient cohorts, MDK RNA expression is significantly associated with the protein abundance of many other proteins, with 11,756 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MDK-associated proteins across cancer lineages are RCN1, ADD3, and CDKN1B. Each is linked with MDK in more than 4 cancer types. Because this analysis shows association rather than direction, both MDK-to-partner and partner-to-MDK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MDK versus RCN1 in LUAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MDK→partner) and Y-score (partner→MDK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RCN1 →	+0.419	+0.961	<.001	<.001	3	5
GBM	ADD3 →	-0.312	-0.784	.001	<.001	3	4
GBM	CDKN1B →	-0.514	-1.292	<.001	<.001	3	4
OV	EHMT1 →	+0.488	+1.620	<.001	<.001	3	4
LUAD	LMNB2 →	-0.225	-0.711	<.001	<.001	3	4
LUAD	MAP1B_S1965 →	+0.736	+1.057	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,756 associations by consensus.

MDK vs RCN1 — LUAD

Explore this scatter interactively →