MDK

Across TCGA cell cohorts, MDK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,843 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MDK-associated GO terms across cancer lineages are Regulation of artery morphogenesis, Positive regulation of artery morphogenesis, and Positive regulation of inflammatory response to wounding. Each is linked with MDK in more than 19 cancer types. Because this analysis shows association rather than direction, both MDK-to-partner and partner-to-MDK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of artery morphogenesis grouped by MDK-low versus MDK-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MDK→partner) and Y-score (partner→MDK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of artery morphogenesis →	+0.256	+5.482	<.001	<.001	3	20
KIDNEY	Positive regulation of artery morphogenesis →	+0.256	+5.482	<.001	<.001	3	20
LIVER	Positive regulation of inflammatory response to wounding →	+0.313	+3.802	<.001	<.001	3	18
SKIN	Behavioral fear response →	+0.613	+4.115	<.001	<.001	3	18
SKIN	Fear response →	+0.629	+4.295	<.001	<.001	3	18
LIVER	Positive regulation of interleukin-12 production →	+0.267	+4.296	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,843 associations by consensus.

Regulation of artery morphogenesis by MDK expression — KIDNEY

Explore this box plot interactively →