MDH1P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MDH1P2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MDH1P2 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MDH1P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MDH1P2 expression acts as an unfavorable survival marker.

BRCA, LUAD, and ESCA are the cancer types where MDH1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.7950.931<.001138view →
LUADOSTertileAll0.5940.823<.001108view →
ESCAOSTertileAll0.2050.911<.00157view →
LIHCOSTertileII,III,IV0.1590.626.00645view →
ACCDFSTertileII,III,IV0.0460.732<.00145view →
COADOSTertileAll0.4350.695.00227view →
THCAOSTertileAll0.9430.983.01918view →
THYMOSTertileAll0.5490.974.00118view →
READDFSTertileIV0.0820.618.01218view →
PCPGDFSTertileAll0.6900.936.00418view →
HNSCOSTertileAll0.2010.605.0339view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration