MDGA2

Across TCGA patient cohorts, MDGA2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,862 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MDGA2-associated genes across cancer lineages are SNRPD3, GRK3, and EIF3L. Each is linked with MDGA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MDGA2-to-partner and partner-to-MDGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MDGA2 versus SNRPD3 in GBM, with a Pearson correlation of 0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MDGA2→partner) and Y-score (partner→MDGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.258	+0.272	.007	.007	3	1
GBM	GRK3 →	+0.485	+0.385	.001	<.001	3	1
GBM	EIF3L →	+0.400	+0.369	<.001	.007	3	1
GBM	POLR2F →	+0.474	+0.402	<.001	<.001	3	1
GBM	SOX10 →	+1.693	+0.494	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.062	+0.460	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,862 associations by consensus.

MDGA2 vs SNRPD3 — GBM

Explore this scatter interactively →