MDGA2

Across TCGA patient cohorts, MDGA2 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,480 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MDGA2-associated proteins across cancer lineages are ARPC5L_S64, ARPP19, and ARPP21. Each is linked with MDGA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MDGA2-to-partner and partner-to-MDGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MDGA2 versus ARPC5L_S64 in GBM, with a Pearson correlation of 0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MDGA2→partner) and Y-score (partner→MDGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARPC5L_S64 →	+0.646	+0.519	<.001	<.001	3	1
GBM	ARPP19 →	+0.337	+0.495	<.001	<.001	3	1
GBM	ARPP21 →	+0.602	+0.435	<.001	<.001	3	1
GBM	ARPP21_S138 →	+1.056	+0.519	<.001	<.001	3	1
GBM	ARPP21_S33 →	+0.907	+0.346	<.001	<.001	3	1
GBM	ART3 →	+0.588	+0.407	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,480 associations by consensus.

MDGA2 vs ARPC5L_S64 — GBM

Explore this scatter interactively →