MDGA2

Across TCGA cell cohorts, MDGA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,771 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MDGA2-associated GO terms across cancer lineages are Neuroblast differentiation, Protein localization to nucleus, and Regulation of telomerase RNA localization to Cajal body. Each is linked with MDGA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MDGA2-to-partner and partner-to-MDGA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuroblast differentiation grouped by MDGA2-low versus MDGA2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MDGA2→partner) and Y-score (partner→MDGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Neuroblast differentiation →	+1.070	+0.914	.002	.003	3	7
STOMACH	Protein localization to nucleus →	+0.057	+0.626	<.001	.002	3	7
STOMACH	Regulation of telomerase RNA localization to Cajal body →	+0.079	+0.696	<.001	.003	3	6
CNS	Host-mediated activation of viral process →	+0.048	+0.612	.001	<.001	3	6
SKIN	Negative regulation of transcription by RNA polymerase III →	+0.102	+0.745	<.001	<.001	3	6
STOMACH	Regulation of protein sumoylation →	+0.080	+0.580	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,771 associations by consensus.

Neuroblast differentiation by MDGA2 expression — SKIN

Explore this box plot interactively →