MDFIC

Across TCGA patient cohorts, MDFIC RNA expression is significantly associated with the protein abundance of many other proteins, with 17,434 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MDFIC-associated proteins across cancer lineages are DPYD, ZYX, and TLN1. Each is linked with MDFIC in more than 8 cancer types. Because this analysis shows association rather than direction, both MDFIC-to-partner and partner-to-MDFIC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MDFIC versus DPYD in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MDFIC→partner) and Y-score (partner→MDFIC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DPYD →	+1.082	+1.223	<.001	<.001	3	9
COAD	ZYX →	+0.474	+0.949	<.001	<.001	3	7
GBM	TLN1 →	+0.405	+1.040	<.001	<.001	3	7
GBM	DAB2 →	+0.532	+0.802	<.001	<.001	3	7
COAD	FLNA →	+0.490	+0.643	<.001	<.001	3	7
GBM	MSN →	+0.417	+0.818	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,434 associations by consensus.

MDFIC vs DPYD — GBM

Explore this scatter interactively →