MCUR1

Across TCGA pan-cancer cohorts, MCUR1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MCUR1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MCUR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MCUR1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

CCRCC, LSCC, and HNSC are the cancer types where MCUR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.453	0.755	.005	32	view →
LSCC	DFS	Tertile	All	0.988	0.913	.011	9	view →
HNSC	OS	Median	All	0.484	1.000	.038	6	view →
GBM	OS	Quartile	All	0.934	0.712	.007	6	view →
PDAC	DFS	Median	IV	0.934	0.250	.024	3	view →
LUAD	OS	Quartile	III,IV	0.827	1.000	.031	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MCUR1–CCRCC (DFS)

Open the CCRCC breakdown →