MCTS2P

Across TCGA pan-cancer cohorts, MCTS2P RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated MCTS2P data layer compared with 2 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher MCTS2P RNA is associated with better overall survival. In most high-consensus cancer types, elevated MCTS2P expression acts as an unfavorable survival marker, although some lineages such as READ and COAD show a favorable association.

READ, CESC, and UCS are the cancer types where MCTS2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	II,III,IV	0.923	0.337	<.001	63	view →
CESC	DFS	Tertile	IV	0.137	0.679	.010	34	view →
UCS	DFS	Median	All	0.291	0.572	.008	24	view →
UCEC	DFS	Tertile	All	0.772	0.889	.001	22	view →
COAD	DFS	Median	All	0.884	0.700	<.001	22	view →
KICH	OS	Quartile	All	0.523	1.000	.014	21	view →
SARC	OS	Tertile	All	0.342	0.645	.008	18	view →
THCA	OS	Quartile	II,III,IV	0.548	0.849	.006	17	view →
ACC	DFS	Median	All	0.424	0.726	.002	16	view →
BRCA	OS	Median	IV	0.560	0.187	.011	16	view →
LIHC	OS	Quartile	II,III,IV	0.325	0.631	.006	14	view →
LUSC	DFS	Quartile	III,IV	0.528	1.000	.025	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

MCTS2P–READ (OS)

Open the READ breakdown →