MCTS1

Across TCGA pan-cancer cohorts, MCTS1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MCTS1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MCTS1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MCTS1 expression acts as an unfavorable survival marker.

LUAD, CCRCC, and GBM are the cancer types where MCTS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.402	0.853	.001	12	view →
CCRCC	DFS	Tertile	II,III,IV	0.500	1.000	.034	6	view →
GBM	OS	Median	All	0.248	0.535	.023	5	view →
PDAC	DFS	Quartile	III,IV	0.536	0.885	.021	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MCTS1–LUAD (DFS)

Open the LUAD breakdown →