MCTS1

Across TCGA cell cohorts, MCTS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,346 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MCTS1-associated GO terms across cancer lineages are Translation reinitiation, Proton-transporting V-type ATPase complex assembly, and Vacuolar proton-transporting V-type ATPase complex assembly. Each is linked with MCTS1 in more than 15 cancer types. Because this analysis shows association rather than direction, both MCTS1-to-partner and partner-to-MCTS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translation reinitiation grouped by MCTS1-low versus MCTS1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCTS1→partner) and Y-score (partner→MCTS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Translation reinitiation →	+0.152	+1.243	<.001	.004	3	16
OESOPHAGUS	Proton-transporting V-type ATPase complex assembly →	+0.142	+0.578	.007	.008	2	11
LUNG_NSCLC_LUSC	Vacuolar proton-transporting V-type ATPase complex assembly →	+0.310	+1.640	<.001	<.001	3	10
LUNG_SCLC	Positive regulation of ferroptosis →	+0.103	+0.487	.002	.001	3	10
KIDNEY	AMP salvage →	+0.139	+0.619	.004	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.186	+1.088	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,346 associations by consensus.

Translation reinitiation by MCTS1 expression — LIVER

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