MCTP1

Across TCGA cell cohorts, MCTP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,586 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MCTP1-associated GO terms across cancer lineages are Positive regulation of cell-substrate junction organization, Hepatocyte growth factor receptor signaling pathway, and Protein localization to site of double-strand break. Each is linked with MCTP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MCTP1-to-partner and partner-to-MCTP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate junction organization grouped by MCTP1-low versus MCTP1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCTP1→partner) and Y-score (partner→MCTP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of cell-substrate junction organization →	+0.114	+1.953	.001	.001	3	10
BREAST	Hepatocyte growth factor receptor signaling pathway →	+0.127	+0.772	.006	.004	3	8
BONE	Protein localization to site of double-strand break →	+0.072	+1.238	.001	.001	3	8
OESOPHAGUS	Modulation of process of another organism →	+0.083	+1.367	.001	.002	3	8
OESOPHAGUS	Host-mediated perturbation of viral process →	+0.105	+1.728	<.001	<.001	3	8
OESOPHAGUS	Positive regulation of focal adhesion assembly →	+0.142	+1.577	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,586 associations by consensus.

Positive regulation of cell-substrate junction organization by MCTP1 expression — LIVER

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