MCRS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MCRS1 mutation is significantly associated with the RNA expression of many other genes, with 793 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MCRS1-associated genes across cancer lineages are LINC00904, RNU1-31P, and STARP1. Each is linked with MCRS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MCRS1-to-partner and partner-to-MCRS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCRS1→partner) and Y-score (partner→MCRS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALINC00904 →+0.228+4.187<.001.00933
KIRCRNU1-31P →+0.217+5.316.002.00632
KIRCSTARP1 →+0.047+6.184<.001.00132
UCECAK4P5 →+0.110+2.192<.001.00832
KIRCBTG3P1 →+0.120+5.256<.001.00632
KIRCOR56A7P →+0.063+5.652<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 793 associations by consensus.

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