Across TCGA cell cohorts, MCRS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,101 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MCRS1-associated GO terms across cancer lineages are Positive regulation of transcription initiation by RNA polymerase II, DNA-templated DNA replication, and DNA replication. Each is linked with MCRS1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MCRS1-to-partner and partner-to-MCRS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCRS1→partner) and Y-score (partner→MCRS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of transcription initiation by RNA polymerase II →	+0.069	+0.684	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.117	+0.831	.004	.002	3	15
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.108	+0.831	.003	.002	3	15
SOFT_TISSUE	DNA replication checkpoint signaling →	+0.172	+0.698	<.001	<.001	3	14
BONE	DNA strand elongation involved in DNA replication →	+0.145	+0.461	<.001	.001	2	15
BLOOD_Lymphoma	Regulation of DNA repair →	+0.068	+0.815	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,101 associations by consensus.

Exploration

MCRS1 survival (RNA) · tumor vs normal (RNA) · all MCRS1 data types