MCRIP2

Across TCGA patient cohorts, MCRIP2 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MCRIP2-associated genes across cancer lineages are RNA5SP138, RNU1-64P, and RNU6-815P. Each is linked with MCRIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCRIP2-to-partner and partner-to-MCRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP138 grouped by MCRIP2-low versus MCRIP2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCRIP2→partner) and Y-score (partner→MCRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP138 →	+0.274	+7.640	<.001	.009	3	1
BLCA	RNU1-64P →	+0.363	+7.640	<.001	.009	3	1
BLCA	RNU6-815P →	+0.277	+7.640	<.001	.009	3	1
BLCA	MIR617 →	+0.312	+7.640	<.001	.009	3	1
BLCA	PMS2P8 →	+0.054	+7.640	<.001	.009	3	1
UCEC	RN7SL275P →	+0.154	+3.344	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

RNA5SP138 by MCRIP2 expression — BLCA

Explore this box plot interactively →