MCRIP2

Across TCGA cell cohorts, MCRIP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,488 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MCRIP2-associated GO terms across cancer lineages are Mitochondrial disulfide relay system, Enzyme-directed rRNA pseudouridine synthesis, and rRNA pseudouridine synthesis. Each is linked with MCRIP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both MCRIP2-to-partner and partner-to-MCRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial disulfide relay system grouped by MCRIP2-low versus MCRIP2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCRIP2→partner) and Y-score (partner→MCRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Mitochondrial disulfide relay system →	+0.138	+0.786	<.001	<.001	3	12
BONE	Enzyme-directed rRNA pseudouridine synthesis →	+0.112	+0.793	.001	<.001	3	12
BONE	rRNA pseudouridine synthesis →	+0.143	+0.819	<.001	<.001	3	11
BLOOD_Myeloma	Protein import into mitochondrial intermembrane space →	+0.140	+0.707	<.001	.002	3	10
SOFT_TISSUE	Muscle organ development →	-0.096	-0.913	<.001	<.001	3	10
LIVER	Regulation of collagen metabolic process →	-0.171	-1.371	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,488 associations by consensus.

Mitochondrial disulfide relay system by MCRIP2 expression — BLOOD_Myeloma

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