Across TCGA pan-cancer cohorts, MCRIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MCRIP1 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MCRIP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MCRIP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where MCRIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	IV	0.495	0.898	.009	32	view →
CCRCC	OS	Median	III,IV	0.924	0.516	.001	14	view →
LUAD	DFS	Median	All	0.741	0.456	.017	5	view →
PDAC	DFS	Median	III,IV	0.544	0.810	.031	2	view →
UCEC	OS	Median	All	0.909	0.985	.027	2	view →
GBM	DFS	Median	All	0.792	0.699	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: MCRIP1 tumor-vs-normal RNA expression · all MCRIP1 data types