Across TCGA patient cohorts, MCRIP1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MCRIP1-associated genes across cancer lineages are MIR6075, MIRLET7A1, and RPL31P33. Each is linked with MCRIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCRIP1-to-partner and partner-to-MCRIP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCRIP1→partner) and Y-score (partner→MCRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6075 →	+0.546	+4.223	<.001	.003	3	1
UCEC	MIRLET7A1 →	+0.826	+4.130	.001	.004	3	1
UCEC	RPL31P33 →	+0.593	+4.184	<.001	.004	3	1
UCEC	ZNF385D-AS2 →	+0.250	+4.567	.005	.001	3	1
UCEC	PRAMEF6 →	+0.071	+4.474	.002	.002	3	1
UCEC	RPL7L1P1 →	+0.160	+4.223	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

MCRIP1 survival (RNA) · tumor vs normal (RNA) · all MCRIP1 data types