Across TCGA patient cohorts, MCMBP mutation is significantly associated with the RNA expression of many other genes, with 4,219 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MCMBP-associated genes across cancer lineages are RNU6-666P, RNU6-693P, and RBPJP6. Each is linked with MCMBP in more than 2 cancer types. Because this analysis shows association rather than direction, both MCMBP-to-partner and partner-to-MCMBP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCMBP→partner) and Y-score (partner→MCMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-666P →	+0.432	+4.927	<.001	.002	3	3
BRCA	RNU6-693P →	+0.351	+5.268	<.001	.003	3	3
PRAD	RBPJP6 →	+0.038	+6.453	<.001	.001	3	2
PRAD	HNRNPH3P1 →	+0.099	+5.490	<.001	.005	3	2
COAD	RNU1-57P →	+0.637	+3.145	<.001	.009	3	2
COAD	RAB5CP2 →	+0.458	+3.665	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,219 associations by consensus.

Exploration

MCMBP survival (RNA) · tumor vs normal (RNA) · all MCMBP data types