Across TCGA cell cohorts, MCMBP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,977 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MCMBP-associated GO terms across cancer lineages are Negative regulation of chromosome segregation, DNA replication, and DNA-templated DNA replication. Each is linked with MCMBP in more than 16 cancer types. Because this analysis shows association rather than direction, both MCMBP-to-partner and partner-to-MCMBP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCMBP→partner) and Y-score (partner→MCMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome segregation →	+0.161	+0.727	<.001	.002	3	17
BLOOD_Myeloma	DNA replication →	+0.117	+1.194	<.001	<.001	3	17
BLOOD_Myeloma	DNA-templated DNA replication →	+0.135	+1.201	<.001	<.001	3	17
LUNG_NSCLC_LUSC	DNA replication initiation →	+0.209	+1.130	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.070	+0.988	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.095	+1.149	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,977 associations by consensus.

Exploration

MCMBP survival (RNA) · tumor vs normal (RNA) · all MCMBP data types