MCM9

Across TCGA patient cohorts, MCM9 protein abundance is significantly associated with the RNA expression of many other genes, with 7,907 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCM9-associated genes across cancer lineages are ZNF207, MTMR4, and SOD2. Each is linked with MCM9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCM9-to-partner and partner-to-MCM9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCM9 versus ZNF207 in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM9→partner) and Y-score (partner→MCM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF207 →	+0.713	+0.773	<.001	<.001	3	2
LSCC	MTMR4 →	+1.026	+0.719	<.001	<.001	3	2
LSCC	SOD2 →	-0.652	-0.455	<.001	.001	3	2
LSCC	FBXO9 →	+0.571	+0.465	<.001	<.001	3	2
BRCA	ZBTB24 →	+0.580	+0.665	.004	.002	3	2
LSCC	SENP6 →	+0.602	+0.539	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,907 associations by consensus.

MCM9 vs ZNF207 — LSCC

Explore this scatter interactively →