MCM9

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MCM9 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,156 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCM9-associated proteins across cancer lineages are DOK3, DPYD_S905, and AMPD3. Each is linked with MCM9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCM9-to-partner and partner-to-MCM9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCM9 versus DOK3 in LSCC, with a Pearson correlation of -0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM9→partner) and Y-score (partner→MCM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCDOK3 →-0.400-0.552<.001<.00132
LSCCDPYD_S905 →-0.687-0.493<.001<.00132
LSCCAMPD3 →-0.476-0.554<.001<.00132
LSCCAMPD3_S87 →-0.895-0.676<.001<.00132
BRCAPNN_S690 →+1.356+0.903<.001<.00132
BRCAARFGAP1_T135 →-0.823-1.121<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,156 associations by consensus.

MCM9 vs DOK3 — LSCC

Per-sample scatter of MCM9 vs DOK3 in LSCC (Pearson r = -0.48).

Explore this scatter interactively →

Exploration