MCM5

Across TCGA patient cohorts, MCM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,355 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCM5-associated proteins across cancer lineages are FEN1, UNG_S23, and MCM2. Each is linked with MCM5 in more than 9 cancer types. Because this analysis shows association rather than direction, both MCM5-to-partner and partner-to-MCM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCM5 versus FEN1 in OV, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM5→partner) and Y-score (partner→MCM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FEN1 →	+0.482	+0.785	<.001	<.001	3	10
LSCC	UNG_S23 →	+1.123	+0.701	<.001	<.001	3	10
LUAD	MCM2 →	+0.780	+0.700	<.001	<.001	3	10
LUAD	MCM2_S41 →	+0.826	+0.632	<.001	<.001	3	10
GBM	MCM3 →	+0.821	+0.621	<.001	<.001	3	10
LUAD	MCM4 →	+0.814	+0.659	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,355 associations by consensus.

MCM5 vs FEN1 — OV

Explore this scatter interactively →