MCM5

Across TCGA patient cohorts, MCM5 protein abundance is significantly associated with the RNA expression of many other genes, with 20,551 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCM5-associated genes across cancer lineages are CENPM, GINS1, and E2F1. Each is linked with MCM5 in more than 9 cancer types. Because this analysis shows association rather than direction, both MCM5-to-partner and partner-to-MCM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCM5 versus CENPM in GBM, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM5→partner) and Y-score (partner→MCM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CENPM →	+1.238	+0.775	<.001	<.001	3	10
LUAD	GINS1 →	+1.406	+0.906	<.001	<.001	3	10
LUAD	E2F1 →	+1.492	+0.879	<.001	<.001	3	10
LUAD	CENPI →	+1.405	+0.905	<.001	<.001	3	10
OV	OIP5 →	+1.065	+0.822	<.001	<.001	3	10
LUAD	MCM4 →	+1.163	+0.777	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,551 associations by consensus.

MCM5 vs CENPM — GBM

Explore this scatter interactively →