MCIDAS

Across TCGA cell cohorts, MCIDAS RNA expression is significantly associated with the go_rna of many other GO terms, with 2,693 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MCIDAS-associated GO terms across cancer lineages are Metaphase/anaphase transition of cell cycle, Regulation of transcription by RNA polymerase I, and Metaphase/anaphase transition of mitotic cell cycle. Each is linked with MCIDAS in more than 8 cancer types. Because this analysis shows association rather than direction, both MCIDAS-to-partner and partner-to-MCIDAS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of cell cycle grouped by MCIDAS-low versus MCIDAS-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCIDAS→partner) and Y-score (partner→MCIDAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Metaphase/anaphase transition of cell cycle →	+0.139	+0.839	<.001	<.001	3	8
LARGE_INTESTINE	Regulation of transcription by RNA polymerase I →	+0.099	+0.917	<.001	<.001	3	8
SOFT_TISSUE	Metaphase/anaphase transition of mitotic cell cycle →	+0.139	+0.875	<.001	<.001	2	9
CNS	Centrosome duplication →	+0.044	+0.399	.003	.006	2	9
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.093	+0.482	.007	.004	3	7
LARGE_INTESTINE	Pre-mRNA catabolic process →	+0.120	+0.790	.007	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,693 associations by consensus.

Metaphase/anaphase transition of cell cycle by MCIDAS expression — SOFT_TISSUE

Explore this box plot interactively →