MCFD2

Across TCGA cell cohorts, MCFD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,472 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MCFD2-associated GO terms across cancer lineages are Cellular response to abiotic stimulus, Cellular response to environmental stimulus, and Positive regulation of cell-substrate junction organization. Each is linked with MCFD2 in more than 12 cancer types. Because this analysis shows association rather than direction, both MCFD2-to-partner and partner-to-MCFD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to abiotic stimulus grouped by MCFD2-low versus MCFD2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCFD2→partner) and Y-score (partner→MCFD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cellular response to abiotic stimulus →	+0.045	+1.154	.003	<.001	3	13
BONE	Cellular response to environmental stimulus →	+0.045	+1.154	.003	<.001	3	13
BONE	Positive regulation of cell-substrate junction organization →	+0.165	+1.000	<.001	<.001	3	13
BONE	Endoderm formation →	+0.212	+0.998	<.001	<.001	3	12
BONE	Fibrinolysis →	+1.628	+1.043	<.001	<.001	3	12
BREAST	Regulation of epidermal growth factor receptor signaling pathway →	+0.078	+1.016	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,472 associations by consensus.

Cellular response to abiotic stimulus by MCFD2 expression — BONE

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