MCF2L2

Across TCGA cell cohorts, MCF2L2 mutation is significantly associated with the RNA expression of many other genes, with 420 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MCF2L2-associated genes across cancer lineages are CD300H, OR13C5, and IFNA14. Each is linked with MCF2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCF2L2-to-partner and partner-to-MCF2L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by MCF2L2-low versus MCF2L2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCF2L2→partner) and Y-score (partner→MCF2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.020	+3.000	<.001	.003	3	2
OVARY	OR13C5 →	+0.012	+3.754	.004	.002	3	2
SOFT_TISSUE	IFNA14 →	+0.032	+5.369	<.001	.004	3	1
SKIN	FUT5 →	+0.022	+3.920	<.001	.005	3	1
SKIN	CRYAA →	+0.048	+3.930	<.001	.003	3	1
SKIN	OR4S2 →	+0.026	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 420 associations by consensus.

CD300H by MCF2L2 expression — LARGE_INTESTINE

Explore this box plot interactively →