MCF2L-AS1

Across TCGA pan-cancer cohorts, MCF2L-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MCF2L-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher MCF2L-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MCF2L-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and LUAD show a favorable association.

KIRP, ACC, and MESO are the cancer types where MCF2L-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.462	0.860	<.001	120	view →
ACC	OS	Tertile	All	0.373	0.857	<.001	101	view →
MESO	DFS	Median	All	0.497	0.280	<.001	63	view →
LGG	OS	Tertile	All	0.741	0.882	<.001	38	view →
ESCA	DFS	Tertile	III,IV	0.287	0.526	.005	33	view →
LUAD	OS	Median	All	0.837	0.730	.013	30	view →
BLCA	OS	Quartile	II,III,IV	0.781	0.641	.006	28	view →
BRCA	OS	Tertile	II,III,IV	0.974	0.929	.007	26	view →
COAD	DFS	Tertile	All	0.627	0.784	.005	26	view →
PAAD	OS	Median	All	0.724	0.527	.015	17	view →
DLBC	DFS	Quartile	IV	0.136	1.000	.024	11	view →
SARC	DFS	Tertile	All	0.589	0.312	.002	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MCF2L-AS1–KIRP (DFS)

Open the KIRP breakdown →