MCF2

Across TCGA patient cohorts, MCF2 protein abundance is significantly associated with the RNA expression of many other genes, with 806 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MCF2-associated genes across cancer lineages are SYNDIG1, MXRA5, and CRISPLD2. Each is linked with MCF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCF2-to-partner and partner-to-MCF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCF2 versus SYNDIG1 in LUAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCF2→partner) and Y-score (partner→MCF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SYNDIG1 →	+0.965	+1.151	.003	<.001	3	1
LUAD	MXRA5 →	+1.752	+1.328	<.001	.008	3	1
LUAD	CRISPLD2 →	+0.843	+1.175	.002	<.001	3	1
LUAD	PDGFRL →	+1.226	+1.222	<.001	<.001	3	1
LUAD	SQLE →	+1.071	+1.022	<.001	.002	3	1
LUAD	SLC39A14 →	+0.808	+1.398	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 806 associations by consensus.

MCF2 vs SYNDIG1 — LUAD

Explore this scatter interactively →