MCF2

Across TCGA patient cohorts, MCF2 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,895 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MCF2-associated proteins across cancer lineages are ALKBH5_S384, GORASP1_S220, and GP1BB_S191. Each is linked with MCF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCF2-to-partner and partner-to-MCF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCF2 versus ALKBH5_S384 in LUAD, with a Pearson correlation of -0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCF2→partner) and Y-score (partner→MCF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ALKBH5_S384 →	-1.218	-1.748	.007	<.001	3	1
LUAD	GORASP1_S220 →	-0.718	-1.667	<.001	<.001	3	1
LUAD	GP1BB_S191 →	+2.783	+1.272	<.001	.002	3	1
LUAD	ABL1_S569 →	-0.490	-1.177	.002	<.001	3	1
LUAD	GPRIN3_S517 →	-1.506	-1.189	<.001	.001	3	1
LUAD	GPS2 →	-0.333	-1.231	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,895 associations by consensus.

MCF2 vs ALKBH5_S384 — LUAD

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