MCEE

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MCEE RNA expression is significantly associated with the protein abundance of many other proteins, with 10,129 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MCEE-associated proteins across cancer lineages are SNRPD2, LMNB2, and PAF1. Each is linked with MCEE in more than 3 cancer types. Because this analysis shows association rather than direction, both MCEE-to-partner and partner-to-MCEE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCEE versus SNRPD2 in GBM, with a Pearson correlation of 0.22.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCEE→partner) and Y-score (partner→MCEE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSNRPD2 →+0.159+0.163.006.00934
PDACLMNB2 →+0.249+0.226<.001<.00134
COADPAF1 →+0.246+0.374<.001.00534
BRCASTMN1_S38 →-0.643-0.335.006.00133
OVPAXX →+0.346+0.371.004.00133
CCRCCARHGEF7_S249 →-0.658-0.341.003.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,129 associations by consensus.

MCEE vs SNRPD2 — GBM

Per-sample scatter of MCEE vs SNRPD2 in GBM (Pearson r = 0.22).

Explore this scatter interactively →

Exploration