Across TCGA patient cohorts, MCCD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,611 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MCCD1-associated proteins across cancer lineages are LYSMD1_S99, PTPN12_S606, and SEC63_T537. Each is linked with MCCD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MCCD1-to-partner and partner-to-MCCD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCCD1→partner) and Y-score (partner→MCCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LYSMD1_S99 →	+0.910	+0.367	<.001	<.001	3	5
GBM	PTPN12_S606 →	-0.487	-0.422	.001	.003	3	4
GBM	SEC63_T537 →	-0.873	-0.540	<.001	<.001	3	4
LUAD	SF3B1_S129 →	+0.462	+0.237	<.001	.002	3	4
LSCC	ZNF609_T746 →	+0.511	+0.205	<.001	.005	3	4
GBM	AHNAK_S5298 →	-0.657	-0.423	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,611 associations by consensus.

Exploration

MCCD1 survival (RNA) · tumor vs normal (RNA) · all MCCD1 data types