Across TCGA patient cohorts, MCCD1 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MCCD1-associated genes across cancer lineages are MIR7976, RNA5SP411, and METTL1P1. Each is linked with MCCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MCCD1-to-partner and partner-to-MCCD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCCD1→partner) and Y-score (partner→MCCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7976 →	+0.850	+3.453	<.001	.009	3	1
UCEC	RNA5SP411 →	+2.206	+3.393	<.001	.007	3	1
UCEC	METTL1P1 →	+0.246	+3.782	.002	.005	3	1
UCEC	MIR3928 →	+1.083	+4.801	<.001	<.001	3	1
UCEC	MIR4764 →	+0.434	+4.226	<.001	.008	3	1
UCEC	MIR4659A →	+0.746	+3.418	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

MCCD1 survival (RNA) · tumor vs normal (RNA) · all MCCD1 data types