Across TCGA cell cohorts, MCCD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,200 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MCCD1-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Negative regulation of telomere maintenance, and Positive regulation of double-strand break repair. Each is linked with MCCD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MCCD1-to-partner and partner-to-MCCD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCCD1→partner) and Y-score (partner→MCCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.081	+0.024	.002	.006	3	6
BLOOD_Lymphoma	Negative regulation of telomere maintenance →	+0.044	+0.077	<.001	.003	3	6
BLOOD_Leukemia	Positive regulation of double-strand break repair →	+0.047	+0.067	.001	.001	3	6
OVARY	Regulation of DNA repair →	+0.042	+0.035	<.001	<.001	3	6
PANCREAS	Chromosome condensation →	+0.109	+0.030	.007	.007	2	6
PANCREAS	Error-free translesion synthesis →	+0.103	+0.038	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,200 associations by consensus.

Exploration

MCCD1 survival (RNA) · tumor vs normal (RNA) · all MCCD1 data types