MCCC2

Across TCGA cell cohorts, MCCC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,342 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MCCC2-associated GO terms across cancer lineages are Quinone biosynthetic process, Ubiquinone biosynthetic process, and Branched-chain amino acid catabolic process. Each is linked with MCCC2 in more than 11 cancer types. Because this analysis shows association rather than direction, both MCCC2-to-partner and partner-to-MCCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Quinone biosynthetic process grouped by MCCC2-low versus MCCC2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCCC2→partner) and Y-score (partner→MCCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Quinone biosynthetic process →	+0.086	+0.868	.001	.003	3	12
BLOOD_Myeloma	Ubiquinone biosynthetic process →	+0.086	+0.868	.001	.003	3	12
LIVER	Branched-chain amino acid catabolic process →	+0.127	+1.389	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.100	+0.937	.006	<.001	3	11
BLOOD_Lymphoma	Nucleic acid transport →	+0.083	+0.982	<.001	<.001	3	10
BLOOD_Lymphoma	RNA transport →	+0.083	+0.982	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,342 associations by consensus.

Quinone biosynthetic process by MCCC2 expression — BLOOD_Myeloma

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