MCCC1-AS1

Across TCGA pan-cancer cohorts, MCCC1-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated MCCC1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MCCC1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MCCC1-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BLCA show a favorable association.

KIRC, UCEC, and STAD are the cancer types where MCCC1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.450	0.729	<.001	120	view →
UCEC	DFS	Median	All	0.791	0.883	<.001	60	view →
STAD	DFS	Quartile	III,IV	0.299	0.581	.005	55	view →
COAD	OS	Tertile	III,IV	0.240	0.746	<.001	48	view →
SKCM	OS	Quartile	III,IV	0.642	0.254	<.001	42	view →
BLCA	OS	Tertile	II,III,IV	0.795	0.639	.006	34	view →
ACC	DFS	Tertile	IV	0.125	0.601	.001	28	view →
PRAD	DFS	Median	All	0.829	0.931	<.001	24	view →
HNSC	DFS	Tertile	All	0.762	0.641	.010	18	view →
LUAD	OS	Median	All	0.458	0.204	.005	15	view →
CHOL	DFS	Median	II,III,IV	0.107	0.546	.008	14	view →
LIHC	DFS	Quartile	All	0.415	0.603	.005	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

MCCC1-AS1–KIRC (DFS)

Open the KIRC breakdown →