MCAT

Across TCGA patient cohorts, MCAT RNA expression is significantly associated with the RNA expression of many other genes, with 18,305 significant associations in total. ACC shows the largest number of these associations.

The most reproducible MCAT-associated genes across cancer lineages are MYG1, XRCC6, and RPS19BP1. Each is linked with MCAT in more than 33 cancer types. Because this analysis shows association rather than direction, both MCAT-to-partner and partner-to-MCAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCAT versus MYG1 in KIRP, with a Pearson correlation of 0.60.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCAT→partner) and Y-score (partner→MCAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	MYG1 →	+0.574	+0.500	<.001	<.001	3	34
ACC	XRCC6 →	+1.391	+1.010	<.001	<.001	3	33
ACC	RPS19BP1 →	+1.019	+1.025	<.001	<.001	3	33
ACC	CDPF1 →	+0.946	+0.967	<.001	<.001	3	33
ACC	PES1 →	+1.364	+0.938	<.001	<.001	3	33
ACC	TIMM13 →	+1.100	+0.881	<.001	.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,305 associations by consensus.

MCAT vs MYG1 — KIRP

Explore this scatter interactively →